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Digital Medicine Mathematical modelling of neuronal learning
Robert Gütig
The Gütig lab uses analytical and numerical modeling techniques to identify the computational principles underlying spike based information processing and learning in central nervous systems and to understand how these principles are implemented by biological processes. Specifically, the lab focuses on the role of action potential timing in sensory…
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Genetics/Genomics Digital Medicine Medical Omics
Sören Lukassen
The Medical Omics lab aims to improve healthcare and basic research by providing artificial intelligence-driven tools for the analysis of large biomedical datasets. For comprehensive insights in disease entities, we aim to include multiple layers of data, such as single-cell RNA sequencing, methylomics data and medical imaging. In close…
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Digital Medicine Computational Medicine
Claudia Langenberg
Common metabolic disorders such as obesity, insulin resistance and type 2 diabetes have both environmental and genetic causes. We now know that many sections of the genome influence the risk of weight gain or adverse fat distribution, in addition to the important roles played by lack of physical activity and excessive intake of high-calorie foods.…
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Digital Medicine Core Unit eHealth and Interoperability (CEI)
Sylvia Thun
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BCRT Epigenetics Immunology Immuno-Epigenetics
Julia Polansky
Not only the DNA sequence – our genome – but also the 3D structure of our genome – the 'epi-genome' – is essential in determining the type and function of a cell. That's why the analysis of the epigenome facilitates deep insights into the developmental history of a cell and its current gene expression profile, but also allows deductions on its…
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Genetics/Genomics Digital Medicine Bioinformatics and Translational Genetics
Dominik Seelow
The main research area of the Bioinformatics and Translational Genetics group is the elucidation of single gene disorders (diseases caused by DNA mutations in a single gene). We are developing user-friendly software that can be used by non-IT specialists. This allows the physicians – who know most about the patients and their disorders – to analyse…
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Digital Medicine Brain Simulation
Petra Ritter
Brain simulation helps us understanding how our brain works – and developing personalized therapies for its diseases
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Digital Medicine Medical Informatics
Fabian Prasser
Further advancing digital medicine requires innovative solutions for integrating healthcare and medical research data. From the perspective of medical informatics, there are important open questions. How can the required collection, integration and analysis of large and heterogeneous data sets be achieved in an efficient, effective and scalable…
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Epigenetics Pneumology Molecular Epidemiology
Irina Lehmann
Research of Molecular Epidemiology Unit at the Berlin Institute of Health and the Charité is focused on epigenetic modifications that occur in close interaction between the individual genetic background and environmental exposure and potentially contribute to increased disease risks. Thereby, we are in particular interested to identify key events…