Genome instability and somatic mosaicism
Ashley Sanders
We sequence cells to understand how genetic mutations form and change cell states in health and disease.
We sequence cells to understand how genetic mutations form and change cell states in health and disease.
The Computational Neurology group develops theory- and data-based methods with the goal of achieving a more comprehensive understanding of neurological system function. In addition to the general goal of a more quantitative neurology, this approach should contribute to a more objective, real-time monitoring with continuous risk assessment and,…
Our research focuses on molecular changes in the development of various tumors. We now want to use bioinformatic and experimental methods to better understand the early development of cancer in order to be able to intervene and prevent it in the long term.
Our motivation is to address fundamental biological questions of human immunology and translate them into innovative therapies. In this respect, the core interest of our laboratory lies in the discovery of new applications of antibodies and B cells to treat and prevent challenging human diseases.
The Medical Omics lab aims to improve healthcare and basic research by providing artificial intelligence-driven tools for the analysis of large biomedical datasets. For comprehensive insights in disease entities, we aim to include multiple layers of data, such as single-cell RNA sequencing, methylomics data and medical imaging. In close…
Rapid advances in molecular biology technologies are leading to a data explosion in biomedical research and clinical diagnostics. The goal of our department is to develop new and targeted ways to analyze and evaluate these data sets in order to implement innovations that benefit patients. For instance, it is desirable to make information from…
The Hedtrich Lab strives to understand and tackle inflammatory and genetic diseases of human epithelia with a current focus on skin, lungs, and intestine. As we firmly believe that human-based models are critical to close the current translational gap in biomedical research, my lab’s research relies on complex human-based organ- and organ-on-chip…
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The Haas group develops and applies novel multimodal single-cell and spatially-resolved technologies to study the complex etiology of hematological cancers and their interaction with the immune system.