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The Hot Topic Seminar on Virtual Reality (VR) in Mental Health aims to provide a platform for the international exchange of ideas between different research groups, (junior) (digital) clinician scientists and international guests. Invited speakers from the Samsung Medical Center in Seoul, South Korea will participate with talks covering, e.g., digital biomarkers and VR-biofeedback in affective disorders. This thematic focus will be complemented by presentations on the development of a VR-exposure therapy in alcohol use disorder, on the assessment of craving in VR using physiological measures as well as on embodiment in VR.